Building a Lab That Actually Works (A Practical Guide for Real Facilities)
I’ve visited a lot of laboratories over the years. Some run like clockwork. Others feel chaotic. The difference usually isn’t the equipment—it’s the planning. Setting up or upgrading a laboratory is one of those decisions that seems straightforward until you’re actually in the middle of it. Suddenly you’re balancing a hundred competing priorities. Budget constraints. […]
Behind Every Great Discovery Is Reliable Equipment
In the scientific world, reproducibility and accuracy are key to progress. One factor often overlooked until something goes wrong is the lab instruments that function perfectly every day. From biotech startups to large pharmaceutical companies, labs depend on a range of sensitive, high-value instruments like incubators, spectrophotometers, shakers, and PCR machines. But what happens when […]
Understanding PFAS and Their Impact
PFAS, or per- and polyfluoroalkyl substances, are a group of man-made chemicals widely used for their durability and resistance to heat, water, and oil. However, their persistence in the environment has earned them the label of “forever chemicals.” PFAS are associated with significant environmental and health concerns, including toxicity and potential endocrine disruption. Why Are […]
The Importance of Intra-Particle Diffusion in Liquid Chromatography
Liquid chromatography (LC) has become an indispensable analytical technique, with high-performance liquid chromatography (HPLC) dominating due to its precision and efficiency. A crucial yet often overlooked factor influencing its performance is intra-particle diffusion. Understanding this phenomenon is essential for optimizing chromatographic separations and achieving accurate results. The Role of Porous Particles in Chromatography Modern HPLC […]
Exhibiting the gas analyzer at the ongoing Tetfund maiden trade fair.
The Ministers of Education and Budget and Planning, along with directors of various parastatals, were visibly impressed during the presentation and live demonstration of the INSCAN Gas Analyzer by Dr. Fred Otuu (University of Nigeria | UNN · Department of Pharmaceutics Ph.D (Chemical Pathology) FNISLT) . This sophisticated device is designed to detect and analyze harmful gases, serving […]
Understanding Lignin in Analytical Chemistry
As industries shift toward sustainable materials, lignin—a complex and renewable biopolymer derived from wood—is gaining attention in fields like analytical chemistry. In-depth analysis of lignin is essential for companies interested in integrating it into products like wood-plastic composites. However, due to lignin’s structural complexity, advanced analytical methods are necessary to unlock its full potential. One […]
Supercritical Fluid Chromatography (SFC): A Powerful analytical Food Analysis Technique
Supercritical Fluid Chromatography (SFC) has gained prominence as a valuable analytical technique in food analysis, providing numerous benefits that enhance accuracy, speed, and depth of results. SFC integrates elements of liquid chromatography (LC) and gas chromatography (GC), using a supercritical fluid—commonly carbon dioxide—as the mobile phase. This fluid exists in a state where it displays […]
Identifying Volatile Organic Compounds (VOCs) Originating from Breath
Advances in Breath Analysis: Novel Method for Identifying Volatile Organic Compounds and Commercial Applications A recent study introduced a novel approach combining robust breath and background collection techniques, which effectively distinguished breath volatile organic compounds (VOCs) from environmental contamination. Using thermo-desorption gas chromatography-mass spectrometry (TD-GC–MS), the researchers identified VOCs against chemical standards, producing a comprehensive […]
Quantification of Amino Acids in Sweat Samples Using HPLC
A recent study explored the significance of quantifying amino acids in small volumes of sweat using high-performance liquid chromatography (HPLC) with fluorescence detection. This method offers a non-invasive and efficient way to screen for diseases by detecting amino acids in minimal sweat samples. Conducted by the Graduate School of Pharmaceutical Sciences at the University of […]
Linear Gradient Method Development Utilising Retention Prediction
INTRODUCTION Developing a liquid chromatography (LC) method is as much an art as it is a science. One might imagine a seasoned chromatography expert creating an optimal method from scratch based solely on the chemistries of the analytes and columns. Such ad hoc method development, however, requires years of experience and may not be feasible […]